CBD does not induce intoxicating feelings, euphoria, or feelings of being high.
CBD is one of over 100 Phyto Cannabinoids identified in Cannabis, which account for more than 40% of the plant’s extract. CBD has a much lower affinity for the CB1 and CB2 receptors than Δ9-tetrahydrocannabidiol (THC), the compound responsible for the intoxicating effect found in Cannabis. However, because of CBDs wide-array of positive pharmacological properties, it has been implicated to have anti-inflammatory, anxiolytic, antipsychotic, and neuroprotective effects. CBD was first discovered in 1940 and has been shown to be well-tolerated in humans with mild adverse events.
CBD has recently been studied clinically in several diseases including addiction, epilepsy, Dravet’s syndrome, Parkinson’s disease (PD), dystonia, and Huntington’s disease (HD). The mechanism of action for CBD is not fully understood due to its complex pharmacology. However, both inflammation and oxidative stress are linked to the pathogenesis of the diseases as well as most ailments, pains, and cancers in the human body.
- CBDs anti-inflammatory and antioxidant properties may be key to its wide range of potentially beneficial effects.
- CBD has been shown to have several molecular targets including antagonism of the CB1 and CB2 receptors.
- CBD is also an agonist of the vanilloid receptor TRPV1 which is implicated in many pain mechanisms including the mechanism of action for onabotulinumtoxinA (BOTOX) in pain associated with chronic migraine.
- CBD has been shown to mediate neurotransmission via the serotonin receptor 5-HT1A. CBDs anti-inflammatory properties are further highlighted by its ability to activate the peroxisome proliferator-activated receptor γ (PPARγ) which is involved in glucose metabolism and lipid storage.
- Moreover, CBD has been reported to act directly on mitochondria by increasing the activity of mitochondrial complexes I-IV.
- CBD treatment decreases the level of the pro-inflammatory cytokines IL-1β, TNF-α, IFN-β, IFN-γ, IL-7, IL-6 all of which are implicated in most progressive neurological diseases such as multiple sclerosis (MS).
- Pre-clinical and clinical evidence for the anti-inflammatory and anti-oxidative highlights the potential of CBD for various beneficial uses.
- CBD s shows great promise in numerous disease states and its role as a neuroprotective agent. New clinical studies are currently on-going in this burgeoning field of CBD science.
Review of Endocannabinoid Facts
The Endocannabinoid System (ECS) operates as a Global Protection System for the body. It fosters a sense of well-being that that is difficult to quantify. It is difficult to describe the benefits of Nano CBD Cosmetics hemp extract products because there are so many different factors in helping people feel better. Poets and song-writers have inadequately attempted for centuries to connect words to convey love.
In the same way, for lack of sufficient words to describe how great our products are, consider the words of science to explain how people feel better about life after using our products. The following report is a sort of a “cliff notes” from which more detailed explanations can be extracted, using this as a guideline.
In the human body there are 12 distinct life-support systems. 11 of the 12 systems are the same ones you are familiar with from high school biology class. There is, however, one more system which was only discovered in Israel in 1988. We now know that the newly discovered Endocannabinoid System acts as a governor and coordinator of all the other body systems you are already familiar with.
The ECS functions through its ability to modulate over 200 different metabolites and enzymes which are ALL essential to healthy, fulfilling, enjoyable life. The ECS coordinates all the other life support systems of the body, and its functions can be broken into 4 major roles of action; eating, cognition, relaxation, protection.
The ECS has two major components which confer its wonderful functioning and ability to affect health through balancing of the body’s 12 life-support systems. The first of the two components are peptides called ligands which trigger the receptors in the ECS. The ligands responsible for activating the ECS are AEA and 2-AG. The receptors of the ECS are CB1, CB2, CB3, CB4, CB5, GABA, and Serotonin receptors.
The reason hemp extracts have been historically sought after, is for their ability to interact with the ECS receptors. ECS receptors are triggered without hemp extracts by the endogenous version of endocannabinoids known as arachidonoylethanolamide (also known as anandamide or AEA). AEA has been touted as the “bliss hormone” because of its ability to bring about a sense of well-being difficult to put to words. The other ligand is scientifically named 2-arachidonylglycerol (2-AG).
In a nutshell, ligands have an array of functions in the body. Ligands are chemical keys which trigger receptors in the brain, spleen, heart, and uterus to name a few. These compounds are created on demand in the phospholipid bilayer of post-synaptic neurons. The function of ligands in the body are to decrease pain, nausea, brain damage, wasting, and anxiety. They also can increase communication of the amygdala and frontal cortex resulting in faster learning, and increased exploratory behavior. Whether decreasing functions or increasing them, ligands work by generally calming neuron function.
The connection between the ECS and Hemp
In the human body the greatest number and density of ECS receptors are found in the hippocampus, cerebellum, and basal ganglia. There are no receptors in the brainstem which is why hemp extract is so safe, even if it is consumed in high doses. Without ECS receptors on the brainstem, there is no risk of breathing suppression or heart rate changes.
Cannabinoid receptors are a class of receptors referred to as G-coupled receptors. They are ubiquitously distributed in all organs and tissues. Different receptor types are found in clusters throughout different areas of the body. Below you will find a summary of receptor types and their functions.
CB1 receptor – Most densely distributed receptor in the brain, also found in adipocytes (fat cells), hepatocytes (liver), skeletal muscle, bone marrow, basophils (immune cells), peripheral nerves, uterus,, adrenals, lungs, bladder, mast cells.
CB1 ligands – 2-AG, AEA, THC, CBD, terpenes
CB1 receptor functions – temperature regulation, emotion, learning, memory, sleep, pain response, language development, musical talent, appetite, protective against neurodegeneration, nausea, and the effects of nerve damage. Animals genetically modified to remove CB1 receptors are: more anxious, depressed, with increased morbidity, increased mortality. They fail to enjoy pleasure, are more afraid, and have both difficulty with learning and unlearning fear
- CB2 receptor – found in immune system and nerve system
- CB2 ligands – AEA, 2-AG, THC, CBD, Echinacea, Caryophyllene
- CB2 receptor functions – protect against osteoporosis, atherosclerosis, pain, liver disease, neurodegeneration, metabolic disorders, inflammation, regulate cytokine activity
- CB3 – a very specific receptor for THC, yet 85% different morphology than CB1 receptors
- CB4 & CB5 – still in early phases of research
The Problem We Solve
Because the Endocannabinoid System (ECS) was undiscovered for so many years, science has now found a new way of looking at the problems of health and disease. Today’s pharmaceutical industry is looking to profit from approved medications that do not interface perfectly with the Endocannabinoid System. Remember the ECS was found in 1988 so it is all very new.
We wish to promote a new daily supplement to prevent a pandemic of Endocannabinoid Deficiency Syndrome. Endocannabinoid Deficiency Syndrome is a suboptimal functioning of the Endocannabinoid System which may be linked to migraines, irritable bowel syndrome, fibromyalgia, anxiety, multiple sclerosis, Huntington’s disease, motion sickness, anorexia, schizophrenia, Parkinson’s disease, and failure to thrive syndrome. There is no doubt as to the effectiveness of Nano CBD from hemp as it relates to supplementing one’s ECS so as to better deal with Endocannabinoid Deficiency Syndrome.
CBD TRENDS WHY CBD Oil is Changing Our World
How Does It Work?
Cannabinoid, or CBD, is a miracle product that everyone has been using to alleviate various conditions, including chronic pain, anxiety, nausea, rheumatoid arthritis, schizophrenia, diabetes, PTSD, alcoholism, strokes and cardiovascular disease, cancer, and other ailments. If you haven’t already heard, Cannabidiol (CBD) is a non-psychoactive component of Cannabis that has a wide range of therapeutic benefits.
CBD is naturally occurring in the Hemp plant and according to the United States own government patent #6,630,507 it supports the nutrition of aging bodies. Cannabidiol is found to have particular benefits as a neuroprotectant, for example in limiting neurological damage following stroke and trauma, or in the treatment of neuro-degenerative diseases, such as Alzheimer’s disease and Parkinson’s disease.
The Hidden Secret
Our earth’s soil is deplete of minerals necessary to carry on optimal life functions. This has been known since 1934 in the Senate Doc 264. Mineral supplements are the only way to maintain optimal abundant health longevity without disease. The Big Bang created the 112 elements in the Periodic Chart.
We need most of them to live long and full of the Life Force we had when we were born. All heat attacks, strokes and aneurisms are caused by a copper and vanadium deficiency. Copper acts on your body like a “Rubber Band”. You want to tighten up your face, boobs and skin in general. Take drops of trace copper minerals.
Life Force: 99 Essential Minerals
There is nothing in a human being’s genes that tells their body that it’s time to start breaking down and getting old or time to get grey hair or its time to get cancer because grandma died of cancer 60 years ago.
Doctors Don’t Want You To Know the Truth
All disease is degenerative. This means that all disease begins as a “nutritional starvation” or depletion that causes individual cells to become unable to rebuild and function. We are killing ourselves by nutritional starvation and when we fall apart and suffer with disease we run to doctors looking for a cure. They only treat the symptoms with drugs, procedures or surgery. Doctors know nothing about healing or prevention because they were not taught any advanced nutrition or biophysics in medical schools.
We are Born with Pre-Cancer Cells
We do not catch cancer from Round Up or asbestos or radiation. We don’t get cancer from anything. The truth is we are ALL born with cancer cells and it is only our immune system that keeps the pre-cancer cells from spreading. Cancer is usually due to a lack of circulation in a fat cell with little blood supply that the same organism has a high acidic condition from eating too much meat protein. Only minerals can build a bullet proof or “Round Up” proof immune system. Organics are as empty as the soil they are grown on.
So… it is not what make up or what we do to our body outside that has anything to do with our natural beauty. It is our life force and what energy we call youth and glowing and vibrant health and healing.
That only comes from essential elements and building blocks of nature, the 90 essential trace, minerals, 12 amino acids and 3 life oils that balance our endocrine system and circadian rhythms and triggers serotonin and endorphins into our bloodstream and we experience joy and healing and abundant health.
A Revolution in Ant-Ageing and Longevity
Our Cells Are Replaced in every tissue, organ, muscle, and our skin.
It is your body and you will have it for the rest of your life.
Cell types in human body: There are over 200 different cell types in the human body, each specialized to carry out a particular function, or form a particular tissue. These cells make up your organs and tissues, as well as help to defend your body as a part of your immune system. Your cells are constantly being replaced as they die. A Few major types of human cell life cycles are:
What is important is… that with Nano sizing CBD and Life Force Rare Earth trace minerals …we have the opportunity to feed our starving cells with all the essential building blocks in ways that we have never been exposed to or experienced in our bodies entire lifetime.
When was the last time you consumed 99 minerals? It never happened!. They are not in organic fruits and veggies. And it is killing us a cell at time and we cannot believe it could be true.
Nano CBD Cosmetics is committed to the science of life and the benefits it brings to health and well being of every living creature. We are all beautiful. Sometimes we need help… and we need it every day of our life if we expect to stay young and beautiful forever. Increasing our bodies cellular life force with Live organic juices each day is part of our regimen.
Our Future Developments
Nano CBD 99 and our planned Life Force 99 are Advanced supplemental support for Ultra Nano Life Force Organic Fruit and Vegetable Juices and Smoothies with 100% Complete mineral, amino acid, oils and vitamins. The Bullet-Proof Holistic Health and Life Insurance.